Susceptibility to Toxoplasmic Retinochoroiditis Is Associated with Hla Alleles Reported to Be Implicated with Rapid Progression to Aids
نویسندگان
چکیده
BACKGROUND/AIMS The frequency of HLA markers associated with rapid progression to AIDS was evaluated in Brazilian patients with AIDS exhibiting or not toxoplasmic retinochoroiditis (TRC). METHODS 98 AIDS patients (25 with TRC, 43 with anti-T. gondii antibodies but without TCR, and 30 without anti-T. gondii antibodies and without TCR) were studied. RESULTS The HLA-B35 was significantly increased in TRC group (p=0.0038). CONCLUSION The presence of HLA-B35 may simultaneously predispose to progression to AIDS and TRC.
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